Tixupharma
Potent & efficient hemosiderin removal
Poxia for microvascular fragility and hematomas
High-performance products for the topical treatment of hemosiderin-related skin discolorations from chronic blood extravasation and acute bruising .
The formulations contain TP7912, potent and highly selective iron chelator that enables targeted detoxification of dermal hemosiderin deposits. In combination with actives that reduce inflammation, prevent reactive pigmentation, and support repair reppresent a comprehensive strategy to restore skin tone and integrity in chronic venous insufficiency, diabetic microangiopathy, rosacea, post-aesthetic sequelae etc.
Chronic Venous Disease (CVD)
In venous insufficiency, repeated capillary leakage causes dermal iron deposits and brownish skin staining, particularly on the lower legs. These marks are often persistent and resistant to conventional care. Hemosiderin removal and skin detox by the selective iron-chelating action provide a high-performance solution that complements standard vascular treatments, thus improving patient quality of life.
Diabetic Vascular Fragility
In diabetes, capillary fragility and oxidative stress contribute to visible hemosiderin spots, particularly on the lower limbs. The pigmentation reflects ongoing microvascular damage and impaired tissue recovery, often worsening with disease progression. The topical strategy supports skin detoxification, improve dermal appearance, and reduce discoloration addressing the consequences of diabetic vasculopathy in a non-invasive, skin-friendly manner.
Phleboctomy Complication
Blood extravasation, the leakage of blood outside of a blood vessel, can be a complication of saphenectomy (removal of the saphenous vein, often for varicose vein treatment). This leakage can occur from the surgical site or from the vein itself during or after the procedure. While some oozing is normal, significant extravasation can lead to complications unless properly treated to produce a fast resolution.
IV Complications & Hospital Care
Intravenous (IV) infusion sites, blood draws, or subcutaneous injections frequently result in bruising, especially in elderly, fragile, or anticoagulated patients. These events often leave behind persistent hemosiderin residues that are slow to resolve. A safe and effective topical option for post-hospital care, supporting faster clearance of discolorations and enhancing skin recovery in clinical settings was still in need.
Post-Aesthetic Sequelae & Rosacea
Bruising following aesthetic treatments and the persistent microvascular damage seen in rosacea can both lead to visible hemosiderin staining. These lesions delay recovery, compromise skin homogeneity, and may negatively impact patient satisfaction. Poxia promotes faster reabsorption of dermal iron residues and supports vascular repair, helping restore a more uniform, healthy-looking complexion. It integrates seamlessly into dermatological and aesthetic aftercare routines.